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Jan 7, 2020

Glossary: Sequence logo

What is a sequence logo?

Sequence logos are created from collections of aligned sequences and consist of stacks of letters representing individual positions in the sequence alignment. The height of each stack indicates the sequence conservation at that position of the alignment measured in bits, and the height of each symbol within the stack reflects its relative frequency at that position.

Sequence logos can be created with tools called sequence logo generators, or sequence logo makers. One such tool is the Sequence Logo Kit. It is browser-based, fast, and highly configurable.

See also
How to align two protein sequences using BLAST?
A step-by-step guide to generating pairwise protein sequence alignments online.
Bioinformatics and software engineering
Do bioinformatics researchers need software engineering training?
Machine learning in bioinformatics
How is machine learning used in bioinformatics?
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